Sunday was one of the most injury-plagued days in NFL history, which could be an indication that a scaled-back offseason and a nixed preseason could cause problems throughout the league early this year. Here’s a rundown of the teams hit the hardest thus far.

8. Indianapolis Colts

They lost safety Malik Hooker and wide receiver Parris Campbell to long-term injuries in Week 2, which is problematic with Marlon Mack, Jack Doyle, and Kemoko Turay already down. It’s not code red yet in Indy, but they can’t afford to lose many more guys.

7. New York Giants

Saquon Barkley was by far and away this team’s best player. Losing him for the season to a torn ACL is crushing, especially with veteran left tackle Nate Solder already a COVID-19 opt-out, and top receivers Sterling Shepard and Golden Tate both hurting as well. Poor Daniel Jones has his work cut out for him hard as a sophomore.

6. Detroit Lions

The secondary has been hammered with Justin Coleman, Desmond Trufant, and high-buzz rookie Jeff Okudah all hurt. Star wide receiver Kenny Golladay is dealing with a hamstring injury, and highly-paid new offensive lineman Halapoulivaati Vaiti has been out with a foot injury. The good news is there might not be much long-term damage, but this spate could still bury a team that is already 0-2.

5. Dallas Cowboys

The famous Dallas offensive line didn’t have Tyron Smith or La’el Collins in Week 2, which is extra tough considering standout center Travis Frederick’s sudden offseason retirement. Throw in the loss of starting tight end Blake Jarwin, and the offense can’t lose many more straws before the camel’s back breaks. And on the other side of the ball, they’ve lost Gerald McCoy, Leighton Vander Esch, Sean Lee, and Anthony Brown already.

4. Philadelphia Eagles

Offseason injuries to offensive linemen Andre Dillard and Brandon Brooks left that unit in awful shape, while they’re missing key front-end defenders Vinny Curry and Javon Hargrave. Throw in Alshon Jeffery’s never-ending foot injury, and it’s no wonder the Eagles are in big trouble early this season.

3. New York Jets

Offensive starters Le’Veon Bell, Connor McGovern, and Breshad Perriman have all been hit, rookie wide receiver Denzel Mims is on injured reserve, and they’re still waiting on Avery Williamson to return from a torn ACL in order to soften the blows that came with C.J. Mosley’s opt-out and the Jamal Adams trade. It’s not easy being Adam Gase or Sam Darnold right now.

2. Denver Broncos

No Drew Lock at quarterback, no Courtland Sutton at wide receiver, no Phillip Lindsay at running back, right tackle Ja’Wuan James is a COVID-19 opt-out, and they’re without Von Miller and A.J. Bouye on defense. This was supposed to be a promising season in Denver, but with those injuries, the team has no shot in the AFC West.

1. San Francisco 49ers

The latest hit came when NFL Network’s Tom Pelissero reported Tuesday that there’s “no clear timetable” for the return of injured edge defender Dee Ford, which is just icing on a cake from hell for a team that is already without defensive star Nick Bosa, quarterback Jimmy Garoppolo, top receiver Deebo Samuel, all-planet tight end George Kittle, key defensive cogs Solomon Thomas and Richard Sherman, and running backs Raheem Mostert and Tevin Coleman. What a mess.

About Brad Gagnon

Brad Gagnon has been passionate about both sports and mass media since he was in diapers -- a passion that won't die until he's in them again. Based in Toronto, he's worked as a national NFL blog editor at theScore.com, a producer and writer at theScore Television Network and a host, reporter and play-by-play voice at Rogers TV. His work has also appeared at CBSSports.com, Deadspin, FoxSports.com, The Guardian, The Hockey News and elsewhere at Comeback Media, but his day gig has him covering the NFL nationally for Bleacher Report.