August 14, 2021; Santa Clara, California, USA; San Francisco 49ers quarterback Trey Lance (5) and quarterback Jimmy Garoppolo (10) warm up before the game against the Kansas City Chiefs at Levi's Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports August 14, 2021; Santa Clara, California, USA; San Francisco 49ers quarterback Trey Lance (5) and quarterback Jimmy Garoppolo (10) warm up before the game against the Kansas City Chiefs at Levi’s Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports

Jimmy Garoppolo and Trey Lance were once considered pillars of the San Francisco 49ers. But a lot can change in two years in the NFL.

Garoppolo is now with the Las Vegas Raiders, and the 49ers recently cut ties with Lance by shipping him to the Dallas Cowboys.

Like Lance, Garoppolo knows what it’s like to be in limbo as a quarterback in the NFL. He spoke on what that means for Lance and the Cowboys during an appearance on NFL Total Access with NFL Network’s Andrew Siciliano.

“Excited for Trey. Just a new opportunity for him,” Garoppolo said in the interview that airs Tuesday at 7 p.m. ET. “Things didn’t work out in San Francisco for whatever reasons, but glad that he gets another shot, man. This league’s all about opportunities, and when you get a fresh one like that, you’ve just got to take advantage of it.

“Everyone has their own path and everything like that. It’s never going to be easy, but it’s how you come out the other end of it. So I’m always excited for him, man. He’s a brother of mine. Always pulling for him.”

Garoppolo also wouldn’t go as far as 49ers head coach Kyle Shanahan in stating that Lance failed in San Francisco.

“I don’t know how the whole thing shook out and everything,” Garoppolo said. “While I was there, Kyle was gonna call the plays for you. You’ve just got to go up there and execute them to the best of your ability.

“Trey’s a brother of mine, man, so like I said before, I’m always pulling for him. I think he’s got a bright future in this league. Dude’s got talent. Just got to get him out there.”

[Pro Football Talk]