DENVER, CO – JULY 18: Starting pitcher Jeremy Guthrie #15 of the Colorado Rockies reacts on the mound before being puled from the game after just two and two-thirds innings of work against the Pittsburgh Pirates at Coors Field on July 18, 2012 in Denver, Colorado. Guthrie gave up six runs on six hits as the Pirates defeated the Rockies 9-6 to win the three game series. (Photo by Justin Edmonds/Getty Images)